• #2-8. Introduction of Energy Vitamin B-Complex



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    Empirically, when deficiency was induced, nervous system abnormalities such as numbness of hands and feet, headache, fatigue, anxiety, gastrointestinal disorders, muscle spasms, and paralysis, decreased immunity, hypoglycemia, and increased insulin sensitivity appeared.


    Hypervitaminosis rarely appears as well.



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    Vitamin B7 (Biotin)


    Vitamin B7 (biotin) is also called vitamin H.


    It has some unfamiliar aspects compared to other B-complex vitamins, and functions are also various.


    In general, it is involved in the process of gluconeogenesis and mainly acts as a coenzyme that converts pyruvate to oxaloacetate.


    It is also involved in fatty acid synthesis.


    It is involved in the synthesis of malonyl-CoA from acetyl-CoA, the first step in the fatty acid synthesis.


    Additionally, it is involved in the metabolism of isoleucine, methionine, and valine among amino acid metabolisms, and these amino acids are converted to succinyl CoA and moved to the TCA cycle (Figure 8).


    Biotin acts on the skin to help relieve symptoms such as atopic dermatitis and eczema, and is also needed to maintain the health of hair and nails.


    Therefore, if it is deficient, symptoms such as hair loss and nail cracking may occur. It is also an important vitamin for the development of children in growth period. Fortunately, there is little deficiency.



    Figure 8. Functions of Vitamin B7 (biotin)



    -To be continued


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