▶ Previous Artlcle:  #5-1. Laser in Clinical Medicine 

 

Like this, the functions of the skin in our body are very diverse, and the typical functions are as follows: The first one is the barrier function.

 

The skin is composed of water and protein and protects the body from external harmful things and critical internal organs from physical damage.

 

The second one is the body temperature control function to maintain a constant body temperature by releasing heat to the outside through sweat when the body temperature rises or by contracting the blood vessels of the skin to prevent from losing heat when the body temperature falls.

 

The third one is the critical immune system function that recognizes and attacks bacteria, fungi, and viruses, localizes the inflammation to prevent it from spreading to the surroundingsand initiates immune modulation to relieve inflammation.

 

The fourth one is the cosmetic function as the skin constitutes the appearance seen by others.

 

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The familiar Bricks (keratinocytes)& Mortar (lipids) theory is applied in order to performthe barrier function, an important part of the role of the skin.

 

Although keratinocytes and lipids both are involved in permeability, the amount of lipids affects permeability more than the number of keratinocytes or the thickness of stratum corneum.

 

Lipids are classified into epidermal polar lipids made fromspinocytes and granulocytes and nonpolar lipids secreted from sebaceous glands, forming a mixture of two lipids in the skin.

 

Lipids consist of ceramide(45%), cholesterol (25%), free fatty acid (15%), and others (15%)including sphingosine, cholesterol sulfate, triglyceride, phospholipid, glycolipid, etc.

 

- To be continued