• #4-6. Types of PDRN/PN and Cosmetic Procedures



    ▶ Previous Artlcle: #4-5. Types of PDRN/PN and Cosmetic Procedures



    In addition, laminin and fibronectin play a significant role in wound healing.


    Figure 4 schematically shows the interaction of ECM, growth factors, and MMP in regeneration of wound sites, displaying the important actions of laminin and fibronectin in wound healing.



    [Ad. ▶HYPERION(Nd:YAG) - Manufacturer: LASEROPTEK(www.laseroptek.com)

    HELIOSⅡ/LOTUSⅡ/HYPERION – Manufacturer: LASEROPTEK(https://www.laseroptek.com/)



    Aging of the skin is essentially chronic damage to the dermis by ultraviolet rays.


    The various rejuvenation procedures using energy-based devices (EBD), laser/light, radiofrequency, high focused ultrasound, which we perform for anti-aging in outpatient clinics, are also to temporarily inflict damage to the dermis with heat.


    When the damaged site is regenerated, collagen is synthesized to induce anti-aging.


    In this context, the skin boosters, especially PDRN/PN, can serve as a huge part of wound healing process.


    In conclusion, PDRN/PN contribute to the regeneration of various intradermic components such as collagen, laminin, and fibronectin, to make the ECM strong and healthy again, which can be led to improvement in sensitive skin, anti-aging effect, and cosmetic improvements.


    In the next issue I'd like to describe the association of PDRN/PN with actual clinical situations, focusing on studies of great clinical value.




    Figure 4. Interactions of ECM, growth factors, and MMP in wound healing. 




    -To be continued

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